Effects of Intravenous Administration of Fat Emulsions and Their Emulsifying Agents

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Effects of Intravenous Administration of Fat Emulsions and Their Emulsifying Agents I. Effects on Clearing Factor Activity, Electrophoretic Pattern and Clotting Time of Blood of Dogs* Preliminary Report

It was observed in this laboratory that intravenous infusions of a cottonseed oil emulsion containing soybean phosphatides and Pluronie1 as emulsifying agents lowered the abnormally high serum lipid levels of patients with idiopathic hyperlipemia and primary hypercholesteremic xanthomatosis (1). It was then found that a single infusion of this emulsion given to fasting human subjects or dogs ca...

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Splenic lipidosis after administration of intravenous fat emulsions.

Spleens showing fatty infiltration and necrosis of the pulp were found at necropsy on several patients who had received intravenous fat emulsions during their terminal illnesses. The postmortem findings are described and the clinicopathological correlation is discussed with special reference to the phenomenon of creaming of the emulsion.

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ژورنال

عنوان ژورنال: Journal of Investigative Dermatology

سال: 1957

ISSN: 0022-202X

DOI: 10.1038/jid.1957.40